Article
Low expression of aging-related NRXN3 is associated with Alzheimer disease: A systematic review and meta-analysis.
Medicine - 1 Jul 2018
Zheng Jun-Juan, Li Wen-Xing, Liu Jia-Qian, Guo Yi-Cheng, Wang Qian, Li Gong-Hua, Dai Shao-Xing, Huang Jing-Fei
Abstract excerpt
BACKGROUND: Alzheimer disease (AD) is a common neurodegenerative disorder with distinct pathological features, with aging considered the greatest risk factor. We explored how aging contributes to increased AD risk, and determined concurrent and coordinate changes (including genetic and phenotypic modifications) commonly exhibited in both normal aging and AD. METHODS: Using the Gene Expression Omnibus (GEO)...
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