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Article

Effect of NR3C2 genetic polymorphisms on the blood pressure response to enalapril treatment.

Pharmacogenomics - 1 Feb 2014

Luo Jian-Quan, Wang Lu-Yan, He Fa-Zhong, Sun Ning-Ling, Tang Gen-Fu, Wen Jia-Gen, Luo Zhi-Ying, Liu Zhao-Qian, Zhou Hong-Hao, Chen Xiao-Ping, Zhang Wei

Abstract excerpt

AIM: The mineralocorticoid receptor (MR; also known as NR3C2) plays important roles in the modulation of blood pressure. The effect of NR3C2 polymorphisms on antihypertensive response to enalapril was investigated. PATIENTS & METHODS: Two hundred and seventy nine essential hypertension patients treated with enalapril were genotyped for two NR3C2 tagSNPs, rs5522 and rs2070950, by Sequenom MassArray™ technology....

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PMID: 24059494
DOI: 10.2217/pgs.13.173

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