Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cross-sectional study of the association of 5 single nucleotide polymorphisms with enalapril treatment response among South African adults with hypertension.

Medicine - 19 Nov 2021

Masilela Charity, Pearce Brendon, Ongole Joven Jebio, Adeniyi Oladele Vincent, Johnson Rabia, Benjeddou Mongi

Abstract excerpt

ABSTRACT: This study investigates the association of 5 single nucleotide polymorphisms (SNPs) in selected genes (ABO, VEGFA, BDKRB2, NOS3, and ADRB2) with blood pressure (BP) response to enalapril. The study further assessed genetic interactions that exist within these genes and their implications in enalapril treatment response among South African adults with hypertension.A total of 284 participants belonging to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antihypertensive Agents
Share to Blood Pressure

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Nitric Oxide Synthase

Share to Pharmacogenetics

Share to Receptor, Bradykinin B2

Share to Receptors, Adrenergic, beta-2

Share to South Africa

Share to Vascular Endothelial Growth Factor A

Source

Open in PubMed Open full text

Identifiers

PMID: 34797313
DOI: 10.1097/MD.0000000000027836
PMCID: PMC8601271

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cross-sectional study of the association of 5 single nucleotide polymorphisms with enalapril treatment response among South African adults with hypertension.PMID 34797313Read ↗

Hypertension in African Populations: Review and Computational Insights.Semantic proximity Read ↗

Pharmacogenomics of Hypertension in Africa: Paving the Way for a Pharmacogenetic‐Based Approach for the Treatment of Hypertension in AfricansSemantic proximity Read ↗

Single Nucleotide Polymorphisms in Amlodipine-Associated Genes and Their Correlation with Blood Pressure Control among South African Adults with Hypertension.Semantic proximity Read ↗

Genetic Variants Associated With Uncontrolled Blood Pressure on Thiazide Diuretic/β-Blocker Combination Therapy in the PEAR (Pharmacogenomic Evaluation of Antihypertensive Responses) and INVEST (International Verapamil-SR Trandolapril Study) Trials.Semantic proximity Read ↗

Non-replication study of a genome-wide association study for hypertension and blood pressure in African Americans.Semantic proximity Read ↗

Genetic Variation in Hydrochlorothiazide Response-Related Genes Among Hypertensive Individuals in Soweto, South Africa.Semantic proximity Read ↗

Pharmacogenomics in Hypertension: Where We Stand TodaySemantic proximity Read ↗

Hypertension pharmacogenetics and limitations in Africa - a focus on the ACE, AGTR1 and CYP2C9 genes.Semantic proximity Read ↗

Hypertension in African Americans.Semantic proximity Read ↗

The effects of genes implicated in cardiovascular disease on blood pressure response to treatment among treatment-naive hypertensive African Americans in the GenHAT study.Semantic proximity Read ↗

Advancing management of hypertension through pharmacogenomicsSemantic proximity Read ↗

Association of genetic variation with blood pressure traits among East Africans.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.