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Article

Roles of STATs signaling in cardiovascular diseases

1 Apr 2012

Abstract excerpt

In cardiac and many other systems, chronic stress activates avfamily of structurally and functionally conserved receptors and their downstream signaling molecules that entail tyrosine, serine or threonine phosphorylation to transfer the messages to the genetic machinery. However, the activation of the Janus kinases (JAKs) and their downstream signal transducer and activator of transcription (STATs) proteins is...

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PMID: 24058760
DOI: 10.4161/jkst.20115

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