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Dancing rhinos in stilettos

5 Apr 2013

Abstract excerpt

A substantial body of evidence has shown that signal transducer and activator of transcription 3 (STAT3) has an important role in the heart in protecting the myocardium from ischemia and oxidative stress. These actions are attributed to STAT3 functioning as a transcription factor in upregulating cardioprotective genes. Loss of STAT3 has been implicated as well in the pathogenesis of heart failure and, in that...

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PMID: 24069556
DOI: 10.4161/jkst.24352

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