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Article

Planar cell polarity: the orientation of larval denticles in Drosophila appears to depend on gradients of Dachsous and Fat.

Development (Cambridge, England) - 1 Oct 2010

Repiso Ada, Saavedra Pedro, Casal José, Lawrence Peter A

Abstract excerpt

The larval ventral belts of Drosophila consist of six to seven rows of denticles that are oriented, some pointing forwards, some backwards. We present evidence that denticle orientation is determined almost entirely by Dachsous and Fat, one of two planar cell polarity systems. If we change the distribution of Dachsous we can alter the polarity of denticles. We suggest that the orientation of the individual...

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Identifiers

PMID: 20826534
DOI: 10.1242/dev.047126
PMCID: PMC2947754

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