Article
Glutathione S-transferase T1, O1 and O2 polymorphisms are associated with survival in muscle invasive bladder cancer patients.
PloS one - 1 Jan 2013
Djukic Tatjana I, Savic-Radojevic Ana R, Pekmezovic Tatjana D, Matic Marija G, Pljesa-Ercegovac Marija S, Coric Vesna M, Radic Tanja M, Suvakov Sonja R, Krivic Biljana N, Dragicevic Dejan P, Simic Tatjana P
Abstract excerpt
OBJECTIVE: To examine the association of six glutathione transferase (GST) gene polymorphisms (GSTT1, GSTP1/rs1695, GSTO1/rs4925, GSTO2/rs156697, GSTM1, GSTA1/rs3957357) with the survival of patients with muscle invasive bladder cancer and the genotype modifying effect on chemotherapy. PATIENTS AND METHODS: A total of 105 patients with muscle invasive bladder cancer were included in the study. The follow-up...
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