Article
Glutathione S-transferase M1 and T1 polymorphisms: susceptibility and outcomes in muscle invasive bladder cancer patients.
European journal of cancer (Oxford, England : 1990) - 1 Sept 2013
Kang Ho Won, Song Phil Hyun, Ha Yun-Sok, Kim Won Tae, Kim Yong-June, Yun Seok-Joong, Lee Sang-Cheol, Choi Yung Hyun, Moon Sung-Kwon, Kim Wun-Jae
Abstract excerpt
BACKGROUND: We investigated whether genetic polymorphisms in the glutathione S transferase mu (GSTM1) and theta (GSTT1) genes modulated risk, disease progression and survival in primary muscle invasive bladder cancer (MIBC). METHODS: GSTM1 and GSTT1 polymorphisms were analysed by multiplex polymerase chain reaction (PCR) using blood genomic DNA in 110 MIBC patients and 220 gender- and age-matched healthy...
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