Article
The prognostic impact of GSTM1/GSTP1 genetic variants in bladder Cancer.
BMC cancer - 23 Oct 2019
Albarakati Nada, Khayyat Dareen, Dallol Asharf, Al-Maghrabi Jaudah, Nedjadi Taoufik
Abstract excerpt
BACKGROUND: The glutathione S-transferases (GSTs) are a superfamily of phase II detoxifying enzymes that inactivates a wide variety of potential carcinogens through glutathione conjugation. Polymorphic changes in the GST genes have been reported to be associated with increased susceptibility to cancer development and anticancer drug resistance. In this study, we investigated the association between genetic...
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