Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The influence of TP53 mutations on the prognosis of patients with early stage non-small cell lung cancer may depend on the intratumor heterogeneity of the mutations.

Molecular carcinogenesis - 1 Feb 2015

Lee Shin Yup, Jeon Hyo-Sung, Hwangbo Yup, Jeong Ji Yun, Park Ji Young, Lee Eun Jin, Jin Guang, Shin Kyung Min, Yoo Seung Soo, Lee Jaehee, Lee Eung Bae, Cha Seung Ick, Kim Chang Ho, Park Jae Yong

Abstract excerpt

A large number of studies have evaluated the impact of TP53 mutations on the prognosis of patients with non-small cell lung cancer (NSCLC); however, the results of these studies are still controversial. Recently, considerable intratumor heterogeneity for genetic alterations has been demonstrated...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenocarcinoma
Share to Carcinoma, Non-Small-Cell Lung

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Heterogeneity

Share to Lung Neoplasms

Share to Prognosis

Share to Sequence Analysis, DNA

Share to Survival Analysis

Share to Tumor Suppressor Protein p53

Source

Identifiers

PMID: 24038464
DOI: 10.1002/mc.22077

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24038464-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 11 closest

The influence of TP53 mutations on the prognosis of patients with early stage non-small cell lung cancer may depend on the intratumor heterogeneity of the mutations.PMID 24038464Read ↗

Multiregion sequencing reveals the intratumor heterogeneity of driver mutations in TP53-driven non-small cell lung cancer.Semantic proximity Read ↗

Mutant-Allele Tumor Heterogeneity, a Favorable Biomarker to Assess Intra-Tumor Heterogeneity, in Advanced Lung AdenocarcinomaSemantic proximity Read ↗

Intratumor heterogeneity and chemotherapy-induced changes in EGFR status in non-small cell lung cancer.Semantic proximity Read ↗

Detection and clinical significance of intratumoral EGFR mutational heterogeneity in Chinese patients with advanced non-small cell lung cancer.Semantic proximity Read ↗

Genetic dissection of intratumor heterogeneity of PD-L1 expression in EGFR-mutated lung adenocarcinoma.Semantic proximity Read ↗

Analysis of intratumor heterogeneity of EGFR mutations in mixed type lung adenocarcinoma.Semantic proximity Read ↗

Intratumor heterogeneity of epidermal growth factor receptor mutations in lung cancer and its correlation to the response to gefitinib.Semantic proximity Read ↗

Frequent intratumoral heterogeneity of EGFR gene copy gain in non-small cell lung cancerSemantic proximity Read ↗

Heterogeneous distribution of EGFR mutations is extremely rare in lung adenocarcinoma.Semantic proximity Read ↗

Intratumoral DNA heterogeneity of small hepatocellular carcinoma.Semantic proximity Read ↗

Intratumor Heterogeneity of ALK-Rearrangements and Homogeneity of EGFR-Mutations in Mixed Lung Adenocarcinoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.