Article
Detection and clinical significance of intratumoral EGFR mutational heterogeneity in Chinese patients with advanced non-small cell lung cancer.
PloS one - 1 Jan 2013
Bai Hua, Wang Zhijie, Wang Yuyan, Zhuo Minglei, Zhou Qinghua, Duan Jianchun, Yang Lu, Wu Meina, An Tongtong, Zhao Jun, Wang Jie
Abstract excerpt
PURPOSE: This study evaluated occurrence and potential clinical significance of intratumoral EGFR mutational heterogeneity in Chinese patients with non-small cell lung cancer (NSCLC). MATERIALS AND METHODS: Eighty-five stage IIIa-IV NSCLC patients who had undergone palliative surgical resection were included in this study. Of these, 45 patients carried EGFR mutations (group-M) and 40 patients were wild-type...
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