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Article

Heterogeneous distribution of EGFR mutations is extremely rare in lung adenocarcinoma.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 1 Aug 2011

Yatabe Yasushi, Matsuo Keitaro, Mitsudomi Tetsuya

Abstract excerpt

PURPOSE: Some studies have shown that epidermal growth factor receptor (EGFR) mutations can be heterogeneously distributed in individual tumors. In this study, we re-evaluated the distribution of EGFR mutations within tumors. PATIENTS AND METHODS: We used multiple approaches, including an analysis of simultaneous dual hot spot mutations, a trans-sectional analysis of individual lung adenocarcinomas, and...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Gene Expression Regulation, Neoplastic

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Source

Identifiers

PMID: 21730270
DOI: 10.1200/JCO.2010.33.3906

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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