Article
Influence of endothelial nitric oxide synthase gene polymorphisms (G894T, 4a4b, T-786C) and hyperhomocysteinemia on the predisposition to acute coronary syndromes.
American heart journal - 1 Mar 2004
Fatini Cinzia, Sofi Francesco, Sticchi Elena, Gensini Francesca, Gori Anna Maria, Fedi Sandra, Lapini Ilaria, Rostagno Carlo, Comeglio Marco, Brogi Daria, Gensini Gianfranco, Abbate Rosanna
Abstract excerpt
BACKGROUND: Nitric oxide is an endothelium-derived relaxing factor that contributes significantly to vascular tone regulation. In this study we investigated the role of endothelial nitric oxide synthase (eNOS) polymorphisms as predisposing factors to acute coronary syndromes (ACS). METHODS: In 477 consecutive patients admitted to the coronary intensive therapy unit of the University of Florence and in 537...
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