Article
Relationship between the A(8002)G intronic polymorphism of pre-pro-endothelin-1 gene and the endothelin-1 concentration among Tunisian coronary patients.
BMC cardiovascular disorders - 16 Nov 2015
Chalghoum Abdelkader, Noichri Yosri, Dandana Azza, Azaiez Sana, Baudin Bruno, Jeridi Gouider, Miled Abdelhédi, Ferchichi Salima
Abstract excerpt
BACKGROUND: Acute coronary syndromes (ACS) are complex and polygenic diseases which are a real problem of public health. These syndromes require multidisciplinary studies to understand the pathogenesis mechanisms. Our study aims to evaluate the endothelin-1 (ET-1) serum concentration in Tunisian coronary compared to controls healthy, as well as the study of the impact of an intronic polymorphism A (8002) G of...
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