Article
A specific interdomain interaction preserves the structural and binding properties of the ModA protein from the phytopathogen Xanthomonas citri domain interaction and transport in ModA.
Archives of biochemistry and biophysics - 1 Nov 2013
Santacruz-Perez Carolina, Pegos Vanessa Rodrigues, Honorato Rodrigo V, Verli Hugo, Lindahl Erik, Barbosa João Alexandre Ribeiro Gonçalves, Balan Andrea
Abstract excerpt
The periplasmic-binding proteins in ATP-binding cassette systems (ABC Transporters) are responsible for the capture and delivery of ligands to their specific transporters, triggering a series of ATP-driven conformational changes that leads to the transport of the ligand. Structurally consisting of two lobes, the proteins change conformation after interaction with the ligand. The structure of the molybdate-binding...
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