Article
The functional principle of eukaryotic molybdenum insertases.
The Biochemical journal - 24 May 2018
Krausze Joern, Hercher Thomas W, Zwerschke Dagmar, Kirk Martin L, Blankenfeldt Wulf, Mendel Ralf R, Kruse Tobias
Abstract excerpt
The molybdenum cofactor (Moco) is a redox-active prosthetic group found in the active site of Moco-dependent enzymes, which are vitally important for life. Moco biosynthesis involves several enzymes that catalyze the subsequent conversion of GTP into cyclic pyranopterin monophosphate (cPMP), molybdopterin (MPT), adenylated MPT (MPT-AMP), and finally Moco. While the underlying principles of cPMP, MPT, and MPT-AMP...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
