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Article

Endogenous tau aggregates in oligodendrocytes of rTg4510 mice induced by human P301L tau.

Journal of Alzheimer's disease : JAD - 1 Jan 2014

Ren Yan, Lin Wen-Lang, Sanchez Laura, Ceballos Carolina, Polydoro Manuela, Spires-Jones Tara L, Hyman Bradley T, Dickson Dennis W, Sahara Naruhiko

Abstract excerpt

Tau belongs to the microtubule-associated family of proteins that maintain cytoskeletal structure by regulating microtubule dynamics. In certain neurodegenerative diseases termed tauopathies, tau is abnormally phosphorylated and accumulates as filamentous inclusions. Transgenic mouse models that...

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Identifiers

PMID: 24028867
DOI: 10.3233/JAD-130986

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24028867-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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