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Article

Proteomics analysis of the neurodegeneration in the brain of tau transgenic mice.

Proteomics - 1 Jun 2002

Tilleman Kelly, Van den Haute Chris, Geerts Hugo, van Leuven Fred, Esmans Eddy L, Moens Luc

Abstract excerpt

Protein tau, a major microtubule-binding protein in the brain, comprises six isoforms generated through alternative mRNA splicing. A dysfunctional form of mutant and normal tau is associated or implicated in the pathogenesis of several neurodegenerative disorders. The neuropathological hallmark o...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12112845
DOI: 10.1002/1615-9861(200206)2:6<656::AID-PROT656>3.0.CO;2-Z

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-12112845-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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