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Article

Ultrastructural neuronal pathology in transgenic mice expressing mutant (P301L) human tau.

Journal of neurocytology - 1 Nov 2003

Lin Wen-Lang, Lewis Jada, Yen Shu-Hui, Hutton Michael, Dickson Dennis W

Abstract excerpt

Transgenic mice expressing mutant (P301L) human tau develop neurofibrillary tangles, amyotrophy and progressive motor disturbance. We present ultrastructural features of neuronal degeneration in this model that suggests involvement of both neurofibrillary and autophagic processes in neurodegenera...

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Identifiers

PMID: 15044841
DOI: 10.1023/B:NEUR.0000021904.61387.95

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15044841-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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