Article
Sugar-sweetened beverage consumption: a risk factor for prevalent gout with SLC2A9 genotype-specific effects on serum urate and risk of gout.
Annals of the rheumatic diseases - 1 Dec 2014
Batt Caitlin, Phipps-Green Amanda J, Black Michael A, Cadzow Murray, Merriman Marilyn E, Topless Ruth, Gow Peter, Harrison Andrew, Highton John, Jones Peter, Stamp Lisa, Dalbeth Nicola, Merriman Tony R
Abstract excerpt
OBJECTIVE: Consumption of high fructose corn syrup (HFCS)-sweetened beverages increases serum urate and risk of incident gout. Genetic variants in SLC2A9, that exchanges uric acid for glucose and fructose, associate with gout. We tested association between sugar (sucrose)-sweetened beverage (SSB) consumption and prevalent gout. We also tested the hypothesis that SLC2A9 genotype and SSB consumption interact to...
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