Article
Genetic risk scores, sex and dietary factors interact to alter serum uric acid trajectory among African-American urban adults.
The British journal of nutrition - 1 Mar 2017
Beydoun May A, Canas Jose-Atilio, Fanelli-Kuczmarski Marie T, Tajuddin Salman M, Evans Michele K, Zonderman Alan B
Abstract excerpt
Serum uric acid (SUA), a causative agent for gout among others, is affected by both genetic and dietary factors, perhaps differentially by sex. We evaluated cross-sectional (SUAbase) and longitudinal (SUArate) associations of SUA with a genetic risk score (GRS), diet and sex. We then tested the interactive effect of GRS, diet and sex on SUA. Longitudinal data on 766 African-American urban adults participating in...
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