Article
Exon and junction microarrays detect widespread mouse strain- and sex-bias expression differences.
BMC genomics - 4 Jun 2008
Su Wan-Lin, Modrek Barmak, GuhaThakurta Debraj, Edwards Stephen, Shah Jyoti K, Kulkarni Amit V, Russell Archie, Schadt Eric E, Johnson Jason M, Castle John C
Abstract excerpt
BACKGROUND: Studies have shown that genetic and sex differences strongly influence gene expression in mice. Given the diversity and complexity of transcripts produced by alternative splicing, we sought to use microarrays to establish the extent of variation found in mouse strains and genders. Here, we surveyed the effect of strain and sex on liver gene and exon expression using male and female mice from three...
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