Article
The relationship between gene isoform multiplicity, number of exons and protein divergence.
PloS one - 1 Jan 2013
Morata Jordi, Béjar Santi, Talavera David, Riera Casandra, Lois Sergio, de Xaxars Gemma Mas, de la Cruz Xavier
Abstract excerpt
At present we know that phenotypic differences between organisms arise from a variety of sources, like protein sequence divergence, regulatory sequence divergence, alternative splicing, etc. However, we do not have yet a complete view of how these sources are related. Here we address this problem, studying the relationship between protein divergence and the ability of genes to express multiple isoforms. We used...
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