Article
New RHCE variant alleles encoding the D- - phenotype.
Transfusion - 1 Nov 2013
Ochoa-Garay Gorka, Moulds Joann M, Cote Jacqueline, Kresie Lesley, Garaizar Adirane, Goldman Mindy, Wynn Polly
Abstract excerpt
BACKGROUND: Variant alleles that do not produce RhCE antigens are rare. Consequently, they pose a challenge to transfusion when found in alloimmunized patients and make blood units valuable when found in donors. STUDY DESIGN AND METHODS: Five index cases and their relatives were studied by both serologic and molecular techniques. Genomic DNA was subjected to microarray genotyping, sequencing, exon scanning,...
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