Article
Identification of a novel frequent RHCE*ce308T variant allele in Chinese D- individuals, resulting in a C+c- phenotype.
Transfusion - 1 Sept 2016
Stegmann Tamara C, Ji Yanli, Bijman Renate, Wang Zhen, Wen Jizhi, Wei Ling, Veldhuisen Barbera, Haer-Wigman Lonneke, Lighthart Peter, Lodén-van Straaten Martin, Luo Guangping, van der Schoot C Ellen
Abstract excerpt
BACKGROUND: The RHCE allele is highly polymorphic; more than 60 variants have been described leading to diminished expression of C, c, E, and e antigens. Not much is known about the prevalence of RHCE variants in the Chinese population. Individuals carrying a variant are at risk to develop alloantibodies in response to mismatched pregnancy or transfusion. In this study, phenotyping and genotyping of the RHCE...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.