Article
A Novel RHCE*cE (c.827C>A) Allele, Containing the Single-Nucleotide Change, Encodes Altered c/E Antigens.
Clinical laboratory - 1 Oct 2023
Wu Chang-Lin, Yi Pin, Tang Bing-Di, Zhang Qiong-Li, Du Xin, Hong Wo-Xia, Ou Zi-Yu, Shao Chao-Peng
Abstract excerpt
The RH blood group system is the most complex with over 50 antigens. So far over hundreds of RhCE variant alleles have been described resulting in weakened and/or partial expression of RhCE antigens [1], some variant Rh phenotypes are caused by exchange of genetic material between the RHD and RHCE genes, resulting in many hybrid genes, other phenotypes result from missense mutations. Variant alleles encode...
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