Article
Molecular characterization of rare D--/D-- variants in individuals of Indian origin.
Blood transfusion = Trasfusione del sangue - 1 Jan 2022
Kulkarni Swati, Mishra Garima, Maru Harita, Parchure Disha, Gupta Debasish, Bajaj Anantpreet Kaur, Sindhwani Sangeeta Pahuja, Chaphekar Anand, Shah Ripal, Férec Claude, Madkaikar Manisha, Fichou Yann
Abstract excerpt
BACKGROUND: Rh antigens are critical in haemolytic disease of the foetus and newborn (HDFN). The D-- phenotype is a rare blood group characterised by the lack of expression of C, c, E and e antigens at the surface of red blood cells because of mutations in both RHCE alleles inactivating the expression of a "normal" protein. The aim of the study was to determine the molecular basis of D-- individuals of Indian...
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