Article
RHCE*cE734C allele encodes an altered c antigen and a suppressed E antigen not detected with standard reagents.
Transfusion - 1 May 2013
Silvy Monique, Barrault Aurélie, Velliquette Randall W, Lomas-Francis Christine, Simon Sophie, Mortelecque Rosanna, Chiaroni Jacques, Bierling Philippe, Noizat-Pirenne France, Bailly Pascal, Tournamille Christophe
Abstract excerpt
BACKGROUND: The RH blood group system has many RHCE variant alleles that have arisen through gene conversion or nucleotide changes. Two probands, with red blood cells (RBCs) that were D+C+E-c+(w) e+ were sent to our laboratories to resolve the weak c expression. STUDY DESIGN AND METHODS: Hemagglutination tests were performed by automated and manual procedures. Genomic DNA analysis was performed by sequencing of...
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