Article
RHCE variants inherited with altered RHD alleles in Brazilian blood donors.
Transfusion medicine (Oxford, England) - 1 Aug 2016
Prisco Arnoni C, Guilhem Muniz J, de Paula Vendrame T A, de Medeiros Person R, Roche Moreira Latini F, Castilho L
Abstract excerpt
BACKGROUND: The high homology and opposite orientation of RH genes promote rearrangements between them and generate a large number of RHD and RHCE variants which can be inherited together. Searching of RHD-CE genotypes predicting partial antigens in donors is of interest in order to find more closely matched donors for African descent patients. This study aimed to evaluate a molecular approach to search for RhCE...
Topics
- Alleles
- Blood Donors
- Brazil
- Female
- Genetic Variation
- Genotype
- Genotyping Techniques
- Humans
- Male
- Rh-Hr Blood-Group System
