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Article

The complex landscape of microRNAs in articular cartilage: biology, pathology, and therapeutic targets

5 Sept 2018

Abstract excerpt

The disabling degenerative disease osteoarthritis (OA) is prevalent among the global population. Articular cartilage degeneration is a central feature of OA; therefore, a better understanding of the mechanisms that maintain cartilage homeostasis is vital for developing effective therapeutic interventions. MicroRNAs (miRs) modulate cell signaling pathways and various processes in articular cartilage via...

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PMID: 30185670
DOI: 10.1172/jci.insight.121630

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