Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

SERPINA3 is a marker of cartilage differentiation and is essential for the expression of extracellular matrix genes during early chondrogenesis

2 Aug 2024

Abstract excerpt

Serine proteinase inhibitors (serpins) are a family of structurally similar proteins which regulate many diverse biological processes from blood coagulation to extracellular matrix (ECM) remodelling. Chondrogenesis involves the condensation and differentiation of mesenchymal stem cells (MSCs) into chondrocytes which occurs during early development. Here, and for the first time, we demonstrate that one serpin,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Adhesion Molecules Research
Share to Osteoarthritis Treatment and Mechanisms
Share to Protease and Inhibitor Mechanisms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 39097037
DOI: 10.1016/j.matbio.2024.07.004

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

SERPINA3 is a marker of cartilage differentiation and is essential for the expression of extracellular matrix genes during early chondrogenesisPMID 39097037Read ↗

Human pluripotent stem cell model of multiple epiphyseal dysplasia with MATN3 mutation identifies altered matrix organisation and upregulation of the cholesterol biosynthesis pathway.Semantic proximity Read ↗

The postnatal role of Sox9 in cartilage.Semantic proximity Read ↗

Human pluripotent stem cell model of multiple epiphyseal dysplasia with <i>MATN3</i> mutation identifies altered Matrix organisation and upregulation of the cholesterol biosynthesis pathwaySemantic proximity Read ↗

New insight on FGFR3-related chondrodysplasias molecular physiopathology revealed by human chondrocyte gene expression profiling.Semantic proximity Read ↗

Critical roles for collagenase-3 (Mmp13) in development of growth plate cartilage and in endochondral ossification.Semantic proximity Read ↗

SOX9 in cartilage development and diseaseSemantic proximity Read ↗

lncRNA ADAMTS9-AS2 Controls Human Mesenchymal Stem Cell Chondrogenic Differentiation and Functions as a ceRNASemantic proximity Read ↗

Altered endochondral bone development in matrix metalloproteinase 13-deficient mice.Semantic proximity Read ↗

Matrix metalloproteinase 13 loss associated with impaired extracellular matrix remodeling disrupts chondrocyte differentiation by concerted effects on multiple regulatory factorsSemantic proximity Read ↗

Matrix Metalloproteinase 3: A Promoting and Destabilizing Factor in the Pathogenesis of Disease and Cell DifferentiationSemantic proximity Read ↗

miR-1247 functions by targeting cartilage transcription factor SOX9.Semantic proximity Read ↗

Morphogenetic and Regulatory Mechanisms During Developmental Chondrogenesis: New Paradigms for Cartilage Tissue EngineeringSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.