Article
Association of Egr-1 and autophagy-related gene polymorphism in men with chronic obstructive pulmonary disease.
Journal of the Formosan Medical Association = Taiwan yi zhi - 1 Aug 2015
Chen Chiung-Zuei, Ou Chih-Ying, Wang Ru-Hsueh, Lee Cheng-Hung, Lin Chien-Chung, Chang Han-Yu, Hsiue Tzuen-Ren
Abstract excerpt
BACKGROUND/PURPOSE: Autophagy is important in cellular homeostasis and control of inflammatory immune response. Increased autophagy has recently been associated with increased cell death and chronic obstructive pulmonary disease (COPD) pathogenesis. Two autophagy regulator genes have been identified: Egr-1 (early growth response), associated with different phenotype expressions in asthma; and, Atg16L1 (autophagy...
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