Article
Association of autophagy related gene polymorphisms with neutrophilic airway inflammation in adult asthma.
The Korean journal of internal medicine - 1 Mar 2016
Pham Duy Le, Kim Seung-Hyun, Losol Purevsuren, Yang Eun-Mi, Shin Yoo Seob, Ye Young-Min, Park Hae-Sim
Abstract excerpt
BACKGROUND/AIMS: Role of autophagy in neutrophil function and the association of autophagy and autophagy related (ATG) gene polymorphisms with asthma susceptibility were suggested. In this study, we investigated the genetic association of ATG5 and ATG7 polymorphisms with asthma risk, severity and neutrophilic airway inflammation. METHODS: We recruited 408 asthma patients and 201 healthy controls. Sputum...
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