Autophagy-related 5 gene mRNA expression and ATG5 rs510432 polymorphism in children with bronchial asthma.

doi:10.1002/ppul.26079

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Article

Autophagy-related 5 gene mRNA expression and ATG5 rs510432 polymorphism in children with bronchial asthma.

Pediatric pulmonology - 1 Nov 2022

Ahmad Enas Sebaey, Diab Safia Mohamed, Behiry Eman Gamal, Bassyoni Shereen El Bassyoni El Said El, Ishak Sally Raafat, Ramadan Abeer

Abstract excerpt

PURPOSE: Bronchial asthma is a common chronic respiratory disease in children with complex pathogenesis, characterized by airway hyper-responsiveness, obstruction, mucus hyperproduction, and airway remodeling. Autophagy is important for cellular physiology, and the ATG5 rs510432 has recently been implicated in several fundamental characteristics of childhood asthma pathogenesis and may play a role in the disease...

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PMID: 35836404
DOI: 10.1002/ppul.26079

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