Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Functional variant in the autophagy-related 5 gene promotor is associated with childhood asthma.

PloS one - 1 Jan 2012

Martin Lisa J, Gupta Jayanta, Jyothula Soma S S K, Butsch Kovacic Melinda, Biagini Myers Jocelyn M, Patterson Tia L, Ericksen Mark B, He Hua, Gibson Aaron M, Baye Tesfaye M, Amirisetty Sushil, Tsoras Anna M, Sha Youbao, Eissa N Tony, Hershey Gurjit K Khurana

Abstract excerpt

RATIONALE AND OBJECTIVE: Autophagy is a cellular process directed at eliminating or recycling cellular proteins. Recently, the autophagy pathway has been implicated in immune dysfunction, the pathogenesis of inflammatory disorders, and response to viral infection. Associations between two genes in the autophagy pathway, ATG5 and ATG7, with childhood asthma were investigated. METHODS: Using genetic and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autophagy-Related Protein 5
Share to Asthma

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, Reporter

Share to HEK293 Cells

Share to Luciferases, Firefly

Share to Microtubule-Associated Proteins

Share to Nasal Mucosa

Share to Ubiquitin-Activating Enzymes

Source

Open in PubMed Open full text

Identifiers

PMID: 22536318
DOI: 10.1371/journal.pone.0033454
PMCID: PMC3335039

Genes

ATG5
ATG7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Functional variant in the autophagy-related 5 gene promotor is associated with childhood asthma.PMID 22536318Read ↗

Autophagy related gene 5 polymorphism rs17587319 (C/G) in asthmatic patients in North Indian population.Semantic proximity Read ↗

Association of autophagy related gene polymorphisms with neutrophilic airway inflammation in adult asthma.Semantic proximity Read ↗

Autophagy-related 5 gene mRNA expression and ATG5 rs510432 polymorphism in children with bronchial asthma.Semantic proximity Read ↗

Autophagy and role in asthmaSemantic proximity Read ↗

Autophagy in airway diseases: a new frontier in human asthma?Semantic proximity Read ↗

Identification of ATPAF1 as a novel candidate gene for asthma in children.Semantic proximity Read ↗

Association between autophagy-related protein 5 gene polymorphisms and epilepsy in Chinese patients.Semantic proximity Read ↗

Autophagy-Related Genes Are Involved in the Progression and Prognosis of Asthma and Regulate the Immune MicroenvironmentSemantic proximity Read ↗

Functional Genetic Variants in ATG10 Are Associated with Acute Myeloid LeukemiaSemantic proximity Read ↗

Association of Egr-1 and autophagy-related gene polymorphism in men with chronic obstructive pulmonary disease.Semantic proximity Read ↗

Promoter polymorphism rs510432 in ATG5 affects the susceptibility of noise-induced hearing loss by altering the binding of C/EBPβ.Semantic proximity Read ↗

Genetic predictors associated with improvement of asthma symptoms in response to inhaled corticosteroids.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.