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Article

Egr-1 Regulates Autophagy in Cigarette Smoke-Induced Chronic Obstructive Pulmonary Disease

1 Oct 2008

Abstract excerpt

BACKGROUND: Chronic obstructive pulmonary disease (COPD) is a progressive lung disease characterized by abnormal cellular responses to cigarette smoke, resulting in tissue destruction and airflow limitation. Autophagy is a degradative process involving lysosomal turnover of cellular components, though its role in human diseases remains unclear. METHODOLOGY AND PRINCIPAL FINDINGS: Increased autophagy was observed...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 18830406
DOI: 10.1371/journal.pone.0003316

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