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Article

Autophagy related gene 5 polymorphism rs17587319 (C/G) in asthmatic patients in North Indian population.

The Journal of asthma : official journal of the Association for the Care of Asthma - 1 May 2024

Kaur Sargeet, Arpna, Jha Durga, Khosla Rajiv, Kaur Manpreet, Parkash Jyoti, Sharma Arti, Changotra Harish

Abstract excerpt

Objective: Genetic background and environmental stimuli play an important role in asthma, which is an individual's hyper-responsiveness to these stimuli leading to airway inflammation. Autophagy Related Gene 5 (ATG5) plays a critical role in the autophagy pathway and has been shown to be involved in asthma. The genetic polymorphisms in the ATG5 have been reported to predispose individuals to asthma. The role of...

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PMID: 38009708
DOI: 10.1080/02770903.2023.2289156

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