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Polymorphisms in autophagy related genes and the coal workers' pneumoconiosis in a Chinese population.

Gene - 20 Oct 2017

Yuan Jiali, Han Ruhui, Esther Ayaaba, Wu Qiuyun, Yang Jingjin, Yan Weiwen, Ji Xiaoming, Liu Yi, Li Yan, Yao Wenxi, Ni Chunhui

Abstract excerpt

Autophagy is an evolutionary conserved intracellular degradation/recycling system that is essential for cellular homeostasis. Dysregulation of this process leads to a number of disorders, including pulmonary fibrosis. However, the genetic association between singe nucleotide polymorphisms of autophagy related genes (ATGs) and the risk of coal workers' pneumoconiosis has not been reported yet. Total of 7 SNPs in...

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Source

Identifiers

PMID: 28844669
DOI: 10.1016/j.gene.2017.08.017

Genes

ATG12
ATG10
ATG5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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