Article
The O‑glycosylation mutant osteopontin alters lung cancer cell growth and migration in vitro and in vivo.
International journal of molecular medicine - 1 Nov 2013
Minai-Tehrani Arash, Chang Seung-Hee, Park Seung Bum, Cho Myung-Haing
Abstract excerpt
Osteopontin (OPN) is an acidic, glycosylated and phosphorylated protein that plays an essential role in determining the aggressiveness and oncogenic potential of several types of cancer, including lung cancer. The OPN function is highly dependent on post-translational modification (PTM) and regulation of the processes that involve OPN can be mediated through glycosylation. However, the connection between OPN...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
