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Article

Aerosol delivery of lentivirus-mediated O-glycosylation mutant osteopontin suppresses lung tumorigenesis in K-ras (LA1) mice.

Cellular oncology (Dordrecht, Netherlands) - 1 Feb 2013

Minai-Tehrani Arash, Chang Seung-Hee, Kwon Jung-Taek, Hwang Soon-Kyung, Kim Ji-Eun, Shin Ji-Young, Yu Kyeong-Nam, Park Sung-Jin, Jiang Hu-Lin, Kim Ji-Hye, Hong Seong-Ho, Kang Bitna, Kim Duyeoul, Chae Chan-Hee, Lee Kee-Ho, Beck George R, Cho Myung-Haing

Abstract excerpt

BACKGROUND: Osteopontin (OPN) is a secreted glycophosphoprotein that has been implicated in the regulation of cancer development. The function of OPN is primarily regulated through post-translational modification such as glycosylation. As yet, however, the relationship between OPN glycosylation and lung cancer development has not been investigated. In this study, we addressed this issue by studying the effect of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23070870
DOI: 10.1007/s13402-012-0107-3
PMCID: PMC13012684

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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