Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

MEF2C exon α: role in gene activation and differentiation.

Gene - 1 Dec 2013

Infantino Vittoria, Convertini Paolo, Menga Alessio, Iacobazzi Vito

Abstract excerpt

Myocyte enhancer factor 2C (MEF2C) belongs to the MEF2 transcription factors. All products of MEF2 genes have a common amino-terminal DNA binding and dimerization domain. All four vertebrate MEF2 gene transcripts are also alternatively spliced. In the present study we identify two novel MEF2C splice variants, named VP and VP2. These variants are generated by the skipping of exon α. The identified α- variants are...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to HEK293 Cells
Share to HeLa Cells
Share to MEF2 Transcription Factors

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Neurogenesis

Share to Protein Isoforms

Share to Tissue Distribution

Share to Transcriptional Activation

Share to Tumor Cells, Cultured

Source

Identifiers

PMID: 24008018
DOI: 10.1016/j.gene.2013.08.044

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

MEF2C exon α: role in gene activation and differentiation.PMID 24008018Read ↗

Tissue-specific splicing of a ubiquitously expressed transcription factor is essential for muscle differentiation.Semantic proximity Read ↗

Altered <i>MEF2</i> isoforms in myotonic dystrophy and other neuromuscular disordersSemantic proximity Read ↗

Identification of MEF2-regulated genes during muscle differentiation.Semantic proximity Read ↗

Characterization of a novel thyroid hormone receptor alpha variant involved in the regulation of myoblast differentiation.Semantic proximity Read ↗

Mutational analysis of the DNA binding, dimerization, and transcriptional activation domains of MEF2C.Semantic proximity Read ↗

Alternative mRNAs encode multiple isoforms of transcription factor AP-2 during murine embryogenesis.Semantic proximity Read ↗

The mouse dead-end gene isoform α is necessary for germ cell and embryonic viabilitySemantic proximity Read ↗

Different levels, but not different isoforms, of the Drosophila transcription factor DMEF2 affect distinct aspects of muscle differentiation.Semantic proximity Read ↗

Mutations within the conserved MADS box of the D-MEF2 muscle differentiation factor result in a loss of DNA binding ability and lethality in Drosophila.Semantic proximity Read ↗

Myocyte enhancer factor 2 acetylation by p300 enhances its DNA binding activity, transcriptional activity, and myogenic differentiation.Semantic proximity Read ↗

Interferon Regulatory Factor-2 Is a Transcriptional Activator in Muscle Where It Regulates Expression of Vascular Cell Adhesion Molecule-1Semantic proximity Read ↗

A splice variant of the ITF-2 transcript encodes a transcription factor that inhibits MyoD activity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.