Article
Alternative mRNAs encode multiple isoforms of transcription factor AP-2 during murine embryogenesis.
Developmental biology - 1 May 1995
Meier P, Koedood M, Philipp J, Fontana A, Mitchell P J
Abstract excerpt
Transcription factor AP-2 has been implicated as an important regulator of gene expression during vertebrate embryogenesis. We report here the cDNA cloning and analysis of mouse embryonic mRNA splice variants encoding four AP-2 isoforms. Isoform 1 is the homolog of the previously known human (HeLa) AP-2. The three new AP-2 isoforms all share the same DNA binding/dimerization domain as isoform 1 but either lack...
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