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Article

Neonatal lupus erythematosus syndrome: analysis of C4 allotypes and C4 genes in 18 families.

Medicine - 1 Mar 1992

Watson R M, Scheel J N, Petri M, Lee L A, Bias W B, McLean R H

Abstract excerpt

We examined 18 families with infants who had neonatal lupus erythematosus (NLE) syndrome to determine whether abnormalities in C4 phenotypes and genotypes were an additional risk factor for this syndrome. Fifteen of 18 mothers of infants with NLE (83%) had C4 null allotypes compared with 36% of population controls (p = less than .001). This increased frequency was due mainly to the presence of C4A null allotypes...

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PMID: 1545698

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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