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Article

Effect of GSTM2-5 polymorphisms in relation to tobacco smoke exposures on lung function growth: a birth cohort study.

BMC pulmonary medicine - 3 Sept 2013

Alexander Melannie, Karmaus Wilfried, Holloway John W, Zhang Hongmei, Roberts Graham, Kurukulaaratchy Ramesh J, Arshad Syed Hasan, Ewart Susan

Abstract excerpt

BACKGROUND: Genetic variation within GSTM2-5 genes may interfere with detoxification of environmental compounds, thereby having a detrimental effect on lung function following exposures such as tobacco smoke. We aim to investigate the influence of variants and associated methylation in the GSTM gene cluster with changes in lung function growth during adolescence. METHODS: Growth in forced expiratory volume...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24004509
DOI: 10.1186/1471-2466-13-56
PMCID: PMC3846453

Genes

GSTM2
GSTM3
GSTM4
GSTM5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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