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Article

Interrogating translational efficiency and lineage-specific transcriptomes using ribosome affinity purification.

Proceedings of the National Academy of Sciences of the United States of America - 17 Sept 2013

Zhou Pingzhu, Zhang Yijing, Ma Qing, Gu Fei, Day Daniel S, He Aibin, Zhou Bin, Li Jing, Stevens Sean M, Romo Daniel, Pu William T

Abstract excerpt

Transcriptional profiling is a useful strategy to study development and disease. Approaches to isolate RNA from specific cell types, or from specific cellular compartments, would extend the power of this strategy. Previous work has shown that isolation of genetically tagged ribosomes (translating ribosome affinity purification; TRAP) is an effective means to isolate ribosome-bound RNA selectively from...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24003143
DOI: 10.1073/pnas.1304124110
PMCID: PMC3780890

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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