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Article

Deep mRNA Sequencing for In Vivo Functional Analysis of Cardiac Transcriptional Regulators

2 Apr 2010

Abstract excerpt

RATIONALE: Transcriptional profiling can detect subclinical heart disease and provide insight into disease etiology and functional status. Current microarray-based methods are expensive and subject to artifact. OBJECTIVE: To develop RNA sequencing methodologies using next generation massively parallel platforms for high throughput comprehensive analysis of individual mouse cardiac transcriptomes. To compare the...

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PMID: 20360248
DOI: 10.1161/circresaha.110.217513

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