Article
Detection of epidermal growth factor receptor mutation in transbronchial needle aspirates of non-small cell lung cancer.
Chest - 1 Jun 2007
Horiike Atsushi, Kimura Hideharu, Nishio Kazuto, Ohyanagi Fumiyoshi, Satoh Yukitoshi, Okumura Sakae, Ishikawa Yuichi, Nakagawa Ken, Horai Takeshi, Nishio Makoto
Abstract excerpt
BACKGROUND: Somatic mutations of epidermal growth factor receptor (EGFR) are closely associated with an objective response to EGFR tyrosine kinase inhibitors. However, it is difficult to obtain sufficient tumor samples from patients with non-small cell lung cancer (NSCLC), so these diagnoses are often made using cytology procedures alone. The aim of this study was to detect EGFR mutations in transbronchial needle...
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