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Article

Malignant pleural effusion supernatants are substitutes for metastatic pleural tumor tissues in EGFR mutation test in patients with advanced lung adenocarcinoma.

PloS one - 1 Jan 2014

Liu Dan, Lu Yachao, Hu Zhenli, Wu Ning, Nie Xiaomeng, Xia Yang, Han Yiping, Li Qiang, Zhu Guanshan, Bai Chong

Abstract excerpt

BACKGROUND: Though the possibility of using malignant pleural effusions (MPEs) as alternatives for metastatic pleural tumor tissues (MPTTs) in epidermal growth factor receptor (EGFR) mutation test has been examined, due to the lack of studies comparing the results in matching MPEs and MPTTs, the clinical value of MPEs for advanced adenocarcinoma patients with pleural effusions is not confirmed. METHODS: EGFR...

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Adenocarcinoma
Adenocarcinoma of Lung
Aged
ErbB Receptors
EGFR gene

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Pleural Effusion, Malignant

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Open in PubMed Open full text

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PMID: 24587142
DOI: 10.1371/journal.pone.0089946
PMCID: PMC3938554

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EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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