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Article

Assessment of the stromal contribution to Sonic Hedgehog‐dependent pancreatic adenocarcinoma

16 Aug 2013

Abstract excerpt

Pancreatic ductal adenocarcinoma (PDAC) remains one of the most lethal malignancies. It is typically detected at an advanced stage, at which the therapeutic options are very limited. One remarkable feature of PDAC that contributes to its resilience to treatment is the extreme stromal activation seen in these tumors. Often, the vast majority of tumor bulk consists of non-tumor cells that together provide a...

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PMID: 23998958
DOI: 10.1016/j.molonc.2013.08.004

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