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Stromal SPOCK 1 supports invasive pancreatic cancer growth

9 May 2017

Abstract excerpt

Pancreatic ductal adenocarcinoma (PDAC) is marked by an abundant stromal deposition. This stroma is suspected to harbor both tumor-promoting and tumor-suppressing properties. This is underscored by the disappointing results of stroma targeting in clinical studies. Given the complexity of tumor-stroma interaction in PDAC, there is a need to identify the stromal proteins that are predominantly tumor-promoting. One...

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PMID: 28486750
DOI: 10.1002/1878-0261.12073

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